為什么在神經(jīng)元退變疾病（neurodegenerative disease）中一些神經(jīng)元被選擇性地指向死亡？最新的一篇文章結(jié)合了果蠅和小鼠的遺傳學(xué)，揭示了蒲肯野細(xì)胞(Purkinje cell)在脊髓小腦性共濟(jì)失調(diào)-1（spinocerebellar ataxia-1）中易受攻擊的秘密。

(Figure 1. Tsuda et al. demonstrate homologous pathways that mediate ataxin-1–induced neurodegeneration in mouse and Drosophila models of SCA-1.)